CV

Version: 2024-01-04 (PDF)

Education and Training

TimeDegreeSchool
01/2021Postdoctoral Researcher, Chemical EngineeringUniversity of Delaware
02/2017Doctor of Philosophy, Chemical EngineeringColumbia University
05/2012Master of Science, Chemical Engineering (Full GPA)Columbia University
06/2011Bachelor of Engineering, Chemical Engineering (First Class Honors)National University of Singapore

Technical Strengths

CategorySkills
CodingPython, R, MATLAB, JavaScript, SQL, Lisp, HTML, LaTeX
ModelingSIMCA, Simulink, COMSOL, NetLogo, Aspen HYSYS
CreativePhotoshop/GIMP, Illustrator/Inkscape, After Effects, FL Studio, Premiere Pro, graphic design, portrait painting, musical composition

Experience

TimePositionAffiliationSupervisors
02/2021–PresentPrincipal Investigator, Associate Fellow, Biopharm Chemometrics and Process Modeling Expert (Recipient of the 2023 Gill Lord Exceptional Impact Award, Multi-Year Recipient of the IPTc Top Performer Award)GSK, Biopharm Drug Substance DevelopmentSameer Talwar, Diana Ritz
06/2017–01/2021Postdoctoral ResearcherUniversity of Delaware, Chemical and Biomolecular EngineeringBabatunde A. Ogunnaike, Kelvin H. Lee
01/2017–05/2017Postdoctoral ResearcherColumbia University, Chemical EngineeringVenkat Venkatasubramanian, Garud Iyengar
09/2011–12/2016Research and Teaching AssistantColumbia University, Chemical EngineeringVenkat Venkatasubramanian, Garud Iyengar
08/2015–12/2015Quantitative Analyst InternPNC BankSanjay Gupta, Brian Burk
05/2010–06/2011Research AssistantSingapore-MIT Alliance, Environmental Sensing and ModelingAdrian Wing-Keung Law

Publications and Presentations

Publications
Yu Luo, Duane A. Stanton, Rachel C. Sharp, Alexis J. Parrillo, Kelsey T. Morgan, Diana B. Ritz, and Sameer Talwar. Efficient optimization of time-varying inputs in a fed-batch cell culture process using design of dynamic experiments. Biotechnology Progress, page e3380, 2023 (PDF)
Yu Luo, Varghese Kurian, Liqing Song, Evan A. Wells, Anne Skaja Robinson, and Babatunde A. Ogunnaike. Model-based control of titer and glycosylation in fed-batch mAb production: Modeling and control system development. AIChE Journal, 69(4):e18075, 2023 (PDF)
Yu Luo, Johanna Vappiani, Keegan Orzechowski, Pramthesh Patel, Daniel Sevin, and Juan Aon. Metabolic rewiring revealed by cell-specific rate analyses from nontargeted exometabolomics during simultaneous consumption of glucose and lactic acid in a cho fed-batch process. Journal of Biotechnology, 359:161–175, 2022 (PDF)
Yu Luo, Varghese Kurian, and Babatunde A. Ogunnaike. Bioprocess systems analysis, modeling, estimation, and control. Current Opinion in Chemical Engineering, 33:100705, 2021 (PDF)
Yu Luo, Robert J. Lovelett, J. Vincent Price, Devesh Radhakrishnan, Kristopher Barnthouse, Ping Hu, Eugene Schaefer, John Cunningham, Kelvin H. Lee, Raghunath B. Shivappa, and Babatunde A. Ogunnaike. Modeling the effect of amino acids and copper on monoclonal antibody productivity and glycosylation: A modular approach. Biotechnology Journal, 16(2):2000261, 2021 (PDF)
Evan Wells, Liqing Song, Madison Greer, Yu Luo, Varghese Kurian, Babatunde A. Ogunnaike, and Anne S. Robinson. Media supplementation for targeted manipulation of monoclonal antibody galactosylation and fucosylation. Biotechnology and Bioengineering, 117(11):3310–3321, July 2020 (PDF)
Venkat Venkatasubramanian and Yu Luo. How much income inequality is fair? Nash bargaining solution and its connection to entropy. In Anindya Chakrabarti, Lukas Pichl, and Taisei Kaizoji, editors, Network Theory and Agent-Based Modeling in Economics and Finance. Springer, Singapore, December 2019 (PDF)
Yu Luo, Garud Iyengar, and Venkat Venkatasubramanian. A one-third advice rule based on a control-theoretic opinion dynamics model. IEEE Transactions on Computational Social Systems, 6(3):576–581, June 2019 (PDF)
Venkat Venkatasubramanian, Yu Luo, and Zhizun Zhang. Control of complex sociotechnical systems: importance of causal models and game theory. Computers & Chemical Engineering, 123:1–11, April 2019 (PDF)
Yu Luo, Garud Iyengar, and Venkat Venkatasubramanian. Social influence makes self-interested crowds smarter: an optimal control perspective. IEEE Transactions on Computational Social Systems, 5(1):200–209, March 2018 (PDF)
Garud Iyengar, Yu Luo, Shivaram Rajgopal, Venkat Venkatasubramanian, and Zhizun Zhang. Towards a financial statement based approach to modeling systemic risk in insurance and banking. Columbia Business School Research Paper, 17(177), July 2017. Available at SSRN. Featured by the “SSRN Top Ten List” in Banking and Insurance, Risk Management and Analysis in Financial Institutions, Risk Management, and Financial Crises categories (PDF)
Yu Luo, Garud Iyengar, and Venkat Venkatasubramanian. Soft regulation with crowd recommendation: coordinating self-interested agents in sociotechnical systems under imperfect information. PLoS ONE, 11(3):e0150343, March 2016 (PDF)
Venkat Venkatasubramanian, Yu Luo, and Jay Sethuraman. How much inequality in income is fair? A microeconomic game theoretic perspective. Physica A: Statistical Mechanics and its Applications, 435:120–138, October 2015. Featured by the “ScienceDirect Top 25 List of Most Downloaded Articles” (PDF)
Richard Bookstaber, Paul Glasserman, Garud Iyengar, Yu Luo, Venkat Venkatasubramanian, and Zhizun Zhang. Process systems engineering as a modeling paradigm for analyzing systemic risk in financial networks. The Journal of Investing, 24(2):147–162, May 2015 (PDF)
Presentations
Yu Luo, Zach Hatzenbeller, Duane Stanton, Alexis Parrillo, Jared Balaich, Sameer Talwar, and Diana Ritz. A less-traveled path for data in bioporcess development: From dynamic experiments to dynamic process models. In Cell Culture Engineering XVIII, Cancun, Mexico, June 2023. Poster presentation
Yu Luo, Duane Stanton, Rachel Sharp, Kelsey Morgan, and Alexis Parrillo. How to win “20 questions” in process development using a design ofdynamic experiments. In IFPAC 2023, North Bethesda, MD, June 2022. Oral presentation
Yu Luo. What does the cell say? How to be a better “listener” and “motivate” cells to work harder through advanced data analytics and modeling approaches. In GSK BPD Science Symposium (Internal), King of Prussia, PA, November 2021. Oral presentation
Yu Luo. Model-based control of biological processes: systems engineering in biomanufacturing. In Chemical Engineering Future Faculty Seminar Series, Santa Barbara, CA, December 2020. Oral presentation
Yu Luo, Varghese Kurian, Janine Buonato, Matthew J. Lazzara, and Babatunde A. Ogunnaike. Model-based approach for multivariate signaling regulation of epithelial-mesenchymal transition in pancreas cancer cells. In AIChE Annual Meeting, San Francisco, CA, November 2020. Oral presentation
Yu Luo. Model-based control of biological processes: systems engineering in biomanufacturing and cancer treatment. In AIChE Annual Meeting, San Francisco, CA, November 2020. Poster presentation
Yu Luo. Model-based control of biological processes: systems engineering in biomanufacturing and cancer treatment. GSK, King of Prussia, PA, October 2020. Invited seminar
Yu Luo, Varghese Kurian, Janine Buonato, Matthew J. Lazzara, and Babatunde A. Ogunnaike. Model-based approach for multivariate signaling regulation of epithelial-mesenchymal transition in pancreas cancer cells. In CSBC Annual Investigators Meeting, Bethesda, MD, September 2020. Poster presentation
Yu Luo, Devesh Radhakrishnan, Evan Wells, Deepro Banerjee, Liqing Song, Varghese Kurian, Anne Robinson, and Babatunde A. Ogunnaike. Control of glycosylation and titer in fed-batch monoclonal antibody production. In Cell Culture Engineering XVII, Tucson, AZ, April 2020. Poster presentation (rescheduled due to COVID-19)
Yu Luo, Devesh Radhakrishnan, Evan Wells, Deepro Banerjee, Liqing Song, Varghese Kurian, Anne Robinson, and Babatunde A. Ogunnaike. Control of glycosylation and titer in fed-batch monoclonal antibody production. In ACS National Meeting & Expo, Philadelphia, PA, March 2020. Oral presentation (rescheduled due to COVID-19)
Yu Luo. Smart biomanufacturing and smarter crowds: a process systems engineering + artificial intelligence approach. Purdue University, West Lafayette, IN, January 2020. Invited seminar
Yu Luo. Smart biomanufacturing and smarter crowds: a process systems engineering + artificial intelligence approach. Clemson University, Clemson, SC, January 2020. Invited seminar
Yu Luo, Devesh Radhakrishnan, Anne Robinson, and Babatunde A. Ogunnaike. Control of glycosylation and titer in fed-batch monoclonal antibody production. In AIChE Annual Meeting, Orlando, FL, November 2019. Oral presentation
Yu Luo. Systems approach to advanced decision-making in chemical engineering, biomanufacturing, and society. In AIChE Annual Meeting, Orlando, FL, November 2019. Poster presentation
Yu Luo. Systems and advanced decisions: from biomanufacturing to opinion dynamics applications. Imperial College London, London, U.K., June 2019. Invited seminar
Yu Luo. Systems and advanced decisions: from biomanufacturing to opinion dynamics applications. Clarkson University, Potsdam, NY, June 2019. Invited seminar
Yu Luo, J. Vincent Price, Robert J. Lovelett, Devesh Radhakrishnan, Kristopher Barnthouse, Eugene Schaefer, John Cunningham, Ping Hu, Kelvin H. Lee, and Babatunde A. Ogunnaike. Multiscale modeling of antibody production and glycosylation for improved upstream process design. In ACS National Meeting & Expo, Orlando, FL, April 2019. Oral presentation
Yu Luo. Systems and advanced decisions: from biomanufacturing to opinion dynamics applications. Stevens Institute of Technology, Hoboken, NJ, March 2019. Invited seminar
Yu Luo. Systems and advanced decisions: from biomanufacturing to opinion dynamics applications. University of Waterloo, Waterloo, ON, Canada, March 2019. Invited seminar
Yu Luo, J. Vincent Price, Robert J. Lovelett, Devesh Radhakrishnan, Kristopher Barnthouse, Eugene Schaefer, John Cunningham, Ping Hu, Kelvin H. Lee, and Babatunde A. Ogunnaike. Multiscale modeling of antibody production and glycosylation for improved upstream process design. In Biotherapeutics and Vaccines Development (Gordon Research Conference), Galveston, TX, January 2019. Poster presentation
Yu Luo, J. Vincent Price, Robert J. Lovelett, Devesh Radhakrishnan, Kristopher Barnthouse, Eugene Schaefer, John Cunningham, Ping Hu, Kelvin H. Lee, Raghunath B. Shivappa, and Babatunde A. Ogunnaike. Multiscale modeling of monoclonal antibody (mAb) production and glycosylation in a Chinese hamster ovary (CHO) cell culture process. In AIChE Annual Meeting, Pittsburgh, PA, October 2018. Oral presentation
Yu Luo. Process systems engineering and artificial intelligence for advanced manufacturing: including applications to biopharmaceuticals. In AIChE Annual Meeting, Pittsburgh, PA, October 2018. Poster presentation
Yu Luo, J. Vincent Price, Robert J. Lovelett, Devesh Radhakrishnan, Kristopher Barnthouse, Eugene Schaefer, John Cunningham, Ping Hu, Kelvin H. Lee, Raghunath B. Shivappa, and Babatunde A. Ogunnaike. Multiscale modeling of monoclonal antibody (mAb) production and glycosylation in a CHO cell culture process. In AMBIC Semiannual Meeting, Fremont, CA, June 2018. Poster presentation
Yu Luo, J. Vincent Price, Robert J. Lovelett, Devesh Radhakrishnan, Kristopher Barnthouse, Eugene Schaefer, John Cunningham, Ping Hu, Kelvin H. Lee, Raghunath B. Shivappa, and Babatunde A. Ogunnaike. Multiscale modeling of monoclonal antibody (mAb) production and glycosylation in a CHO cell culture process. In Cell Culture Engineering XVI, Tampa, FL, May 2018. Poster presentation
Yu Luo, Garud Iyengar, and Venkat Venkatasubramanian. Control with soft feedback in social systems: mathematical principles, empirical evidence, and applications. In AIChE Annual Meeting, Minneapolis, MN, November 2017. Oral presentation
Yu Luo, Ashutosh Nanda, Shivaram Rajgopal, Vinay Ramesh, Zhizun Zhang, Catherine Zhao, and Venkat Venkatasubramanian. A data-driven early warning system for mining accidents. In Global Congress on Process Safety, San Antonio, TX, March 2017. Oral presentation
Yu Luo, Garud Iyengar, and Venkat Venkatasubramanian. The control of self-interested agents: learning from nature’s wisdom of crowds. In AIChE Annual Meeting, San Francisco, CA, November 2016. Oral presentation. Finalist and travel grant recipient for the AIChE CAST Division Director’s Student Presentation Award
Yu Luo, Richard Bookstaber, Paul Glasserman, Garud Iyengar, Zhizun Zhang, and Venkat Venkatasubramanian. Process systems engineering beyond chemical plants: signed digraph as a modeling tool for analyzing systemic risk in financial networks. In AIChE Annual Meeting, San Francisco, CA, November 2016. Oral presentation
Yu Luo. Process systems engineering beyond chemical plants. In AIChE Annual Meeting, San Francisco, CA, November 2016. Poster presentation
Yu Luo, Garud Iyengar, and Venkat Venkatasubramanian. Soft regulation: coordinating distributed self-interested agents in sociotechnical systems. In AIChE Annual Meeting, Atlanta, GA, November 2014. Oral presentation

Teaching

TimeRoleCourseAffiliation
Spring 2016Student LecturerManaging Systemic Risk in Complex Systems (Graduate)Columbia University
Fall 2015Student LecturerManaging Systemic Risk in Complex Systems (Graduate)Columbia University
Spring 2012Teaching AssistantMolecular Phenomena (Undergraduate)Columbia University
Fall 2011Teaching AssistantThermodynamics (Undergraduate)Columbia University

Professional Service

TimeRoleOrganization
12/2012–PresentReviewerComputers and Chemical Engineering. Recognized as an outstanding reviewer
  Biotechnology and Bioengineering
  IEEE Conference on Decision and Control
  The Canadian Journal of Chemical Engineering
  AIChE Journal
  Scientific Reports
  Frontiers Physiology
  Metabolic Engineering Communications
  Biotechnology Journal
  Chemical Engineering Research and Design
11/2014–PresentMember, Session ChairAIChE
12/2012–05/2017Webmaster, Event Assistant, Graphic DesignerColumbia University, Center for the Management of Systemic Risk